If you are struggling with chronic pain, one of the safest and most effective options could be marijuana. Medical marijuana is becoming one of. By Winston Peki. With the widespread legalization of medical marijuana, many people turn to the drug for a more natural pain relief method. As a natural. What are the best cannabis strains for chronic pain? studies focus on for pain relief are cannabidiol (CBD) and tetrahydrocannabinol (THC).
THC: Which Pain Relief? or CBD Better is for
Critical Mass is one of the very best strains of Indica for pain. It is high in CBD, and is also great for relieving stress and anxiety.
This is a great strain for totally relaxation without losing your cognitive abilities. Harlequin is a Sativa dominant variety, but a CBD dominant strain. This strain is the best of both worlds without the psychoactive properties of most Sativa dominant strains.
Cannatonic is a hybrid strain that is CBD dominant. It is excellent for pain, and can also be used for stress or muscle spasms. Unlike pain, fighting fatigue requires a THC dominant strains. Therefore, there are not any indica strain recommendations for fatigue here. However, it is always possible to combine a high energy strain with your favorite CBD dominant pain-fighting strain to see what results you get. There is an Indica dominant strain that goes by the same name, but Sativa is the ticket for fighting fatigue.
White Widow is one of the most popular strains on planet earth. This strain is great for a burst of energy that will get you moving, yet the CBD content helps to limit the psychoactive effects. There are different kinds of focus that Marijuana can give you. Cinex is a strain that will give you a clear headed ability to hyper-focus. This strain also boosts creativity. For those that tend to get paranoid from THC, this might heighten that sensation, so be careful. This strain gives you a burst of clarity and creativity, while the CBDs from the indica mellow out the euphoria and help the body feel good.
Great for fibro fog and chronic pain. True OG is the CBD dominant strain for those that have thoughts racing through the brain, yet want to calm the noise and focus on a single task. This strain is also great for pain and insomnia, which makes it a great all-around strain for Fibromyalgia. When you need energy, you look for a THC dominant strain, but when you are looking to go to sleep, you need a CBD dominant strain.
Therefore, the recommendations here are all Indicas and hybrid varieties with a high CBD content. Obviously it much more complicated and involved than that, but that is a good rule of thumb. These two Indica recommendations are great for putting you to sleep. Both are CBD dominant. Afghan Kush is for when you want to pass out. It is a heavy CBD dominant strain, and it will definitely do the trick. Big Bud is another CBD dominant strain that will definitely put you to sleep.
However, Big Bud is better at fighting pain that Afghan Kush both are pretty good at it. Big Bud is the perfect strain for when your pain will not let you sleep. In every cannabis plant, there is a unique mixture of hundreds of plant compounds, comprised of phytocannabinoids, terpenes, and flavonoids. Research suggests that these compounds too have an influence on our neurochemistry, and together they may work synergistically, producing better improvements in pain relief than anyone would produce on its own.
This research supports the idea that it is best to use the whole cannabis plant, with CBD, THC, and the natural medley of additional compounds. This harmony between the various plant chemicals found in marijuana is colloquially referred to as the entourage effect. The most well-studied compounds found in the marijuana plant that support the idea of the entourage effect are THC and CBD, which have been found to work differently together than when separate.
Using these two compounds in concert has been shown to help mitigate side effects and enhance efficacy, with CBD plus THC showing more benefit for some conditions than THC alone. It has also been found to extend the half-life of THC, which may help to extend the pain-relieving benefits. This has allowed the use of higher doses of THC in clinical trials for the treatment of pain caused by multiple sclerosis, peripheral neuropathic pain, intractable cancer pain, and rheumatoid arthritis.
When used in concert, a greater efficacy in treating these types of pain have been observed. Every strain of bud that you can purchase at a dispensary will be labeled with its THC and CBD content, which can be helpful when choosing which strain to choose for pain relief.
CBD has been found to exhibit enhancements in treating pain both when used on its own and when used in combination with THC. When used alone, CBD is largely best for inflammatory pain, such as that caused by arthritis or injuries. In one animal study on arthritis pain, it was found that the topical application of CBD led to a reduction in inflammation and pain.
Another animal study found that CBD helps to reduce neuropathic pain through the suppression of chronic inflammation. CBD does not directly bind to the receptors found in the endocannabinoid system but rather works to modulate the effects of the endocannabinoids the cannabinoids found naturally in our bodies as well as working as a CB1 receptor antagonist.
The main mechanism by which CBD is thought to help mediate pain is by reducing inflammation , largely by blocking inflammatory mediators. It is also believed to potentiate glycine receptors, which help to regulate pain at the spinal level.
This suppresses both neuropathic and inflammatory pain. THC is used clinically for the treatment of pain and studies find it helps relieve central and neuropathic pain. It is also used to help reduce pain in cancer, AIDS, and fibromyalgia patients, for which resistance to other pain treatments have been found. The mode of action for THC is as a partial CB1 receptor agonist, which means that it will bind to these receptors but not fully which leads to the variability in effects documented when THC is present with other CB1 agonists, antagonists or both.
It has been found to impact the serotonergic, dopaminergic, and glutamatergic systems — an action which may contribute to its pain-relieving benefits.
Additionally, THC has been found to act as an anti-inflammatory agent. While human studies have found benefits from the use of THC, CBD, and whole-plant marijuana in relieving pain, much of the evidence for this use comes from user reports and surveys. When searching for the best cannabis strains for pain relief, you will first want to consider how much THC and CBD is found in the strain. This is because CBD can help to mediate the side effects of THC while also providing additional anti-inflammatory and analgesic properties.
One example would be if you are experiencing inflammation, yet you are wanting to go about your day normally, without the psychotropic effects of THC.
Other times you may be in enough pain that you would like something that takes your mind off the pain while also offering pain relief. In one survey , participants reported that indicas helped more than sativas when it came to headaches, joint pain, neuropathy, and spasticity.
Users also reported indicas to be more helpful when it comes to sleep and sedation. Lastly, there are countless user reports on specific strains of weed that have been found to be powerful for relieving pain. While some of these strains are high CBD, indica strains, some strains of weed used for pain do not fall into this category. It may be that the other cannabinoids, terpenes, and flavonoids have come together in a harmonious balance that leads to strong pain-relieving properties.
There are limited studies examining the effect of CBD alone on pain in humans. When it comes to CBD only studies, the majority are preclinical or animal studies. That said, the research conducted thus far, along with countless user reports, suggests that CBD itself may be able to help relieve pain.
Activation of cannabinoid receptors has been linked to the inhibition of pain. The exact mechanisms of action are still being researched, however, CBD has been found to increase the levels of endocannabinoids in the body, specifically anandamide. It is plausible that this increase in endogenous endocannabinoids could have an impact on pain. Another study suggests that CBD in rats induced suppression of chronic inflammation and neuropathic pain through potentiating glycine receptors.
Here we will examine the limited scientific evidence, along with theories relating to the use of CBD for pain. Neuropathic pain, also known as nerve pain, is a unique type of pain that is caused by injured, dysfunctional, or irritated nerves.
This pain tends to be chronic and severe, and with no known cure or remedy, every individual is left to try numerous strategies to find something that works for them. Some of the most common sources of neuropathy include diabetes, injury, cancer, infections, alcoholism, and autoimmune disorders.
The ECS is controlled by chemicals that our body produces called endocannabinoids. Our endocannabinoids are responsible for keeping our most critical biological functions in balance such as sleep, appetite, the immune system, pain and more. When the body gets out of balance and moves into a state of stress, endocannabinoids go to work to fix the problem. The pharmaceutically active components in the cannabis plant mimic endocannabinoids. It does this by working with the endocannabinoid system, which controls pain and inflammation.
Can you think of a disease that does not come with inflammation and pain? The cannabis plant happens to be one of the most if not the most pharmacologically active plants on the planet, containing over active chemicals.
The unique active components of cannabis are called cannabinoids , which are found alongside active chemicals called terpenoids we also refer to them as terpenes and flavonoids. These chemical components work together to provide a wide variety of therapeutic benefits to the human body. Various levels and combinations of cannabinoids, terpenoids and flavonoids provide many benefits to the human body including: It is the combination of varying levels of cannabinoids, terpenoids and flavonoids that seem to make the most effective medicine for specific symptoms and dis-eases — the isolated components appear to be less effective but nonetheless still therapeutic.
Cannabis has been found to ease general pain, chemo induced neuropathy, and nausea, as well as increase appetite and reverse wasting.
THC vs. CBD for Pain: The Differences and Interactions
We'll take a look at two compounds, CBD vs THC, and compare them on a number of different levels. It's also available in oils, edibles, tinctures, capsules, and more. between cells and have roles in pain, immune function, stress, sleep , to name a few. They can provide relief from several of the same conditions. CBD vs THC the great debate. Should you use one or both? For pain I would take a full spectrum CBD product. A full spectrum CBD product contains CBD and. More research is required to establish the connection between CBD and It is clear that CBD oil has a number of functions in pain relief and.