Now, we are considering the cannabis plant. Does anyone have any feedback for us in connection with Absence Seizures and CBD's &/or THCA meds?. I am curious if anyone has tried the new CBD oil to control their epilepsy. I have read many great things about it really controlling seizures and maybe trying it. For those adults treating with nonpsychoactive CBD, what dosage did you start with? Specifically for 22%/05% CBD/THC ratio with 22 mg dosage for pound .
Oil Absence HempWorx Epilepsy and CBD
FDA-approved drugs are usually deemed effective or ineffective based on large-scale clinical trials that study hundreds to thousands of patients over several years. These studies followed only a few hundred patients in all, and for only a few months. Second, the studies in question did not include placebo controls. That is, all of the study participants were given actual CBD, and they knew they were getting it.
Other research has found that the placebo effect can be especially strong when it comes to marijuana. In one study, patients of families who moved to Colorado for cannabis oil treatment were twice as likely to report a substantial reduction in seizures as those patients who already lived in the state. The third major reason the studies were deemed insufficient involves drug interactions.
This drug interaction makes it impossible to say whether reduced seizure incidence seen in study participants was due to CBD by itself or whether it was simply the result of those other medications staying in the system for longer stretches. The good news is that higher-quality randomized clinical trials that examine the effectiveness of CBD oil for epilepsy are underway some have even been completed , and the results should be published sometime this year.
In the meantime, there are a few things to keep in mind if you or your child suffers from intractable seizures and you're considering trying cannabis oil. First is that, as we've written before, medical marijuana or cannabis products are not subject to the same regulations as FDA-approved drugs.
Even items sold through a dispensary or a mail-order service may be mislabled or contaminated. Second, as noted above, even with design flaws that might have made CBD appear more effective than it really is, the available studies found that for most patients the drug did not work better than existing anti-epilepsy medication in treatment-resistant patients.
That is, it reduced seizures by only a small amount in most patients. Third is the available evidence on side effects: In the best-done study, 79 percent of participants reported adverse events from cannabis oil, including diarrhea and fatigue, but only 3 percent of them dropped out of the study.
That adverse event rate is not small; according to a letter in the journal Lancet Neurology, it's higher than the side effect rate for other epilepsy drugs.
But by most expert accounts, the low drop-out rate suggests cannabis oil is safe—for short term use, at least. For longer-term use, there are some causes for concern—namely that studies suggest extended or chronic cannabis consumption can cause lasting harm to the developing brain; it's at least possible that those harms might be as pronounced for CBD as they are for traditional forms of the drug.
Still, treatment-resistant epilepsy is a debilitating condition that can dramatically impede a person's quality of life. In severe cases, it can be life-threatening. So with those caveats in mind, the bottom line is this: If you live somewhere you can legally obtain CBD, are suffering from intractable seizures, and all other approved therapies have failed, you might want to try cannabis.
But you should only do so under the supervision of your regular doctor. I'm a scientist-turned-journalist, covering the intersection of science, policy, and consumer health.
I have an abiding passion for good storytelling and verifiable data. I live in Manhattan with my husband and our cat. When I'm not working, I love museums, parks, and visiting my people in New Jersey. Please call Member Services at Welcome to Consumer Reports. You now have access to benefits that can help you choose right, be safe and stay informed. Unfortunately, these hard-to-treat epilepsies are associated with an increased risk of premature death.
Anecdotal evidence suggests that cannabis oil may help some of these people control their seizures and potentially save their lives.
A small number of studies have shown that adding cannabis oil to existing medication may be effective in devastating, hard-to-treat epilepsy in children and adolescents. One of those people is year-old Billy Caldwell. Billy was in the news recently after the cannabis oil prescribed for him was confiscated at Heathrow airport by the authorities. Billy was seizure-free for more than days when taking the oil, but his seizures started again when his cannabis oil was withdrawn.
The home secretary, Sajid Javid, was persuaded to intervene and one of the seven bottles of cannabis oil was returned , with a day licence to administer the medicine. In a similar case, six-year-old Alfie Dingle, who suffers from severe epilepsy, had been successful treated with cannabis oil in the Netherlands.
But cannabis oil that contains THC at higher levels more than 0. THC is a schedule 1 drug , that is to say, it is deemed to have no medicinal value. There is good evidence in robust human clinical trials that CBD is of benefit for specific epilepsies, such as Dravet syndrome and Lennox Gastaut syndrome. An advantage for the pharmaceutical industry is that these rare diseases with no cure can be fast-tracked for drug development.
If so, Epidiolex is likely to be available in US by late European approval is likely to follow. It should be noted that Epidiolex is designed as standardised oral solution of pure plant-derived CBD. It is not the same as the non-standardised, viscous CBD oils that contain varying amounts of CBD and can be purchased in health food shops. There is currently no good evidence that formulations of CBD oil or indeed cannabis oil are as effective on epilepsy seizures.
Equally, there is no robust evidence — just anecdotal reports — that THC helps reduce epilepsy seizures human. In [animal studies], THC has weak overall effects in reducing seizures and has also been shown to be a less effective anticonvulsant than CBD.
Can Cannabis Oil Really Treat Seizures?
And I would not want to try switching/mixing different anti-seizure medication. I was just wondering if anyone has had any luck with CBD oil, or has any advice for. Although CBD oil has become a trendy cure-all, treatment of epilepsy is the only use that has garnered significant scientific evidence. Cannabidiol (CBD) oil has become the hot new product in states that use for CBD with the most evidence after usefulness in epilepsy, but.